Duration:
1 Semester | Turnus of offer:
each winter semester | Credit points:
6 |
Course of studies, specific field and terms: - Master MLS 2009 (Module part of a compulsory module), neuroscience, 1st semester
- Master CLS 2010 (module part), computational life science / life sciences, 3rd semester
|
Classes and lectures: - Immunology (seminar, 2 SWS)
- Immunology (lecture, 2 SWS)
| Workload: - 60 Hours in-classroom work
- 120 Hours private studies
| |
Contents of teaching: | - Lecture: Introduction to immunology
- Cells of the innate immune system
- Innate immune system: pathogen recognition
- Complement and inflammation
- Introduction into the adaptive immune system
- Antigen-presentation and T cell activation
- Immunological memory
- Immune system and infektion I: bacteria, worms, fungi
- Immune system and infektion II: Viruses
- Signal transduktion in immune cells
- Organs and tissues of the immune system, homing
- Immunpathogenesis I: allergy and asthma
- Immunpathogenesis II: autoimmune diseases
- Immunprivileged Organs
- Hematopoiesis and hematopoietic stem cells
- Experimental and clinically applied biologicals
- Seminar: PCR
- ELISA/ELISPOT
- Flow cytometry I: FACS-Analysis
- Flow cytometry II: MACS, FACS-Sort
- Flow cytometry III: Practical course at the ISEF (MACS, Analysis, Sort)
- Conventional and confocal microscopy
- Methods in signal transduction
- Migration: transwell assay; adhesion test etc.
- 2-Photon microscopy
- Animal models in life science
- Genetically modified mice I: conventional transgenics and KO mice
- Genetically modified mice II: conditional KO und Knock In Mice
| |
Qualification-goals/Competencies: - Students are able to:
- Name cells of the immune system and allocate their functions
- Name organs that belong to the immune system and allocate their functions
- Name mechanisms, cells and molecules of the innate and adaptive immune system and allocate their functions during bacterial, viral and fungal infections
- Name and allocate functions of molecules important for B cell -T cell co-cooperation
- Name and allocate the functions of molecules and antigen-presenting cells important for T cell activation and differentiation
- Name molecules of the complement system and allocate their functions for immune protection and immune diseases
- Name structure and function of the distinct antibody classes
- Name and allocate functions of molecules important for homing and migration of immune cells
- Name and allocate functions of molecules important for the initiation and resolution of inflammation
- Name the functions of immunological memory
- Name molecules and mechanisms involved in the development of B cell and T cell memory
- Describe the principal sequence of an immune reaction during infection and after vaccination
- Name genetic, molecular and cellular disturbances of the immune system relevant for immune deficiency, autoimmune and allergic diseases
- Describe the basic mechanisms of signal transduction in immune cells
- Name mechanisms and molecules involved in hematopoiesis
- Name and explain immunological methods
- Present and discuss scientific data
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Grading through: |
Responsible for this module: - Prof. Dr. rer. nat. Rudolf Manz
Teachers: - Prof. Dr. rer. nat. Rudolf Manz
- Prof. Dr. med. Jörg Köhl
- Prof. Dr. rer. nat. Marc Ehlers
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Literature: - Janeway, Travers, Walport, Shlomchik: Immunologie - Spektrum Akademischer Verlag
- : Original- und Übersichtsartikel
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Language: |
Notes:(Part of the module MZ5110) |
Letzte Änderung: 17.7.2019 |
für die Ukraine