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Module Guide since WS 2016/17

Modul LS4131-KP04

Basics of Membrane Biophysics (Membiop04)

Duration:


1 Semester
Turnus of offer:


each summer semester
Credit points:


4
Course of studies, specific field and terms:
  • Master Biophysics 2023 (Module part of a compulsory module), life sciences, 2nd semester
  • Master Molecular Life Science 2023 (optional subject), structure biology, 2nd semester
  • Master MLS 2018 (optional subject), structure biology, 2nd semester
  • Master MLS 2016 (optional subject), structure biology, 2nd semester
Classes and lectures:
  • Basics of Membrane Biophysics (exercise, 1 SWS)
  • Basics of Membrane Biophysics (lecture, 2 SWS)
Workload:
  • 75 Hours private studies
  • 45 Hours in-classroom work
Contents of teaching:
  • Importance and function of cell membranes: structure, physical function and dynamic models
  • Basics of the membrane components
  • Thermodynamic self-assembling of lipids and reconstitution techniques
  • Transmembrane and intrinsic membrane potentials
  • Mechanical properties of lipid membranes
  • Physical basics of membrane transport mechanisms
  • Investigations using lipid monolayer
  • Electrical and optical experiments using planar lipid bilayers
  • Examples for interaction mechanisms between peptides/ proteins and planar membranes
  • Spectroscopic methods on membranes and membrane proteins
  • Light and force microscopy on membranes and membrane proteins
Qualification-goals/Competencies:
  • Constituents and composition of biological membranes
  • Physical role and function of membrane lipids and proteins
  • Mechanical and electrical properties of membranes
  • Various methods to investigate reconstituted and natural membranes
Grading through:
  • written exam
Responsible for this module:
  • Prof. Dr. rer. nat. Thomas Gutsmann
Teachers:
  • Prof. Dr. rer. nat. Thomas Gutsmann
  • Prof. Dr. rer. nat. Andra Schromm
  • Dr. Christian Nehls
Literature:
  • Adam, P. Läuger, G. Stark: Physikalische Chemie und Biophysik - Springer-Verlag, 4. Auflage 2003
  • W. Hanke, R. Hanke: Methoden der Membranphysiologie - Spektrum Akademischer Verlag, Auflage 1997
  • Ole G. Mouritsen: Life - As a Matter of Fat - Springer 2005, ISBN 987-3-540-23248-3
  • Thomas Heimburg: Thermal Biophysics of Membranes - Whiley-VCH 2007, ISBN 978-3-527-40471-1
  • Lukas K. Buehler: Cell Membranes - Garland Science 2016, ISBN 978-0-8153-4196-3
Language:
  • English, except in case of only German-speaking participants
Notes:

Prerequisites for the module:
- nothing

Prerequisites for admission to the written examination:
- succesful participation in the exercises

Module exam:
- LS4131-L1: Membrane-Biophysics, written exam, 90 min, 100 % module grade

Letzte Änderung:
16.4.2021