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Module Guide since WS 2016/17

Modul EW4170-KP05

Systems Biology (SystBio)

Duration:


1 Semester
Turnus of offer:


each winter semester
Credit points:


5
Course of studies, specific field and terms:
  • Master Nutritional Medicine 2023 (compulsory), Nutritional Sciences, 1st semester
  • Master MLS 2018 (optional subject), life sciences, 1st semester
  • Master MLS 2016 (optional subject), interdisciplinary competence, 1st semester
  • Master Nutritional Medicine 2019 (compulsory), life sciences, 1st semester
Classes and lectures:
  • Introduction to classic and translational system biology (exercise, 2 SWS)
  • Introduction to classic and translational system biology (lecture, 2 SWS)
Workload:
  • 60 Hours in-classroom work
  • 70 Hours private studies
  • 20 Hours exam preparation
Contents of teaching:
  • Introduction to the genome and proteome of cellular systems
  • Networks: cellular, genetic, gene-regulatory networks, interactomes
  • Analysis of dynamical systems: fixed points, bifurcations and feedback
  • Bioinformatic analysis of “Omics” data
  • Introduction to public databases: e.g. STRING, Gene Expression Omnibus, TCGA, KEGG, Reactome, MSigDB
  • Exercises: computer lab for analysis of dynamical systems and cellular pathways in R
  • Exercises: Practical exercises on the analysis of dynamical systems and cellular signaling pathways.
  • Exercises on the solution of differential equations
Qualification-goals/Competencies:
  • The students can explain the principles of signal transduction in the cell
  • The students can relate to the genome, transcriptome, interactome and proteome
  • They can analyse and characterize dynamical systems
  • They know common methods to analyse high-throughput data
  • Lab work will enable the students to continue studying this subject on their own
Grading through:
  • written exam
Responsible for this module:
Teachers:
Literature:
  • Marian Walhout, Marc Vidal, Job Dekker: Handbook of Systems Biology: Concepts and Insights - (Englisch) Gebundene Ausgabe – 15. November 2012
  • Edda Klipp, Wolfram Liebermeister, Christoph Wierling, Axel Kowald;: Systems Biology: A Textbook - Englisch) Taschenbuch – 20. April 2016
  • Yoram Vodovotz and Gary: An Translational Systems Biology, Concepts and Practice for the Future of Biomedical Research
Language:
  • offered only in English
Notes:

Prerequisites for the module:
- nothing

Prerequisites for admission to the written examination:
- successful participation in the exercises

Module exam:
- EW4170-L1: Systembiology, written exam, 90 min, 100 % module grade

Letzte Änderung:
27.9.2021