Duration:
1 Semester | Turnus of offer:
each summer semester | Credit points:
8 |
Course of studies, specific field and terms: - Master CLS 2023 (compulsory), MML with specialization in Life Science, 2nd semester
- Bachelor Molecular Life Science 2024 (compulsory), Chemistry, 4th semester
- Bachelor MLS 2018 (compulsory), Chemistry, 4th semester
- Bachelor MLS 2016 (compulsory), Chemistry, 4th semester
- Master CLS 2016 (compulsory), MML with specialization in Life Science, 2nd semester
- Bachelor Biophysics 2016 (compulsory), biophysics, 4th semester
- Master CLS 2010 (optional subject), computational life science / life sciences, 2nd semester
- Bachelor MLS 2009 (compulsory), life sciences, 4th semester
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Classes and lectures: - Biophysical Chemistry (practical course, 3 SWS)
- Biophysical Chemistry (exercise, 1 SWS)
- Biophysical Chemistry (lecture, 3 SWS)
| Workload: - 80 Hours in-classroom work
- 160 Hours private studies
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Contents of teaching: | - Lecture topics:
- What is Biophysical Chemistry?
- Basics of NMR spectroscopy
- Basics of mass spectrometry
- Theoretical calculation of molecules - Quantum mechanics or molecular mechanics?
- Basics of chemical thermodynamics
- Thermodynamics of ligand binding
- Basics of chemical kinetics
- Basics of enzyme kinetics
- Molecular Mechanics
- Practical works:
- NMR, Molecular Modeling, experiments with a focus on thermodynamics and kinetics
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Qualification-goals/Competencies: - Acquire basic knowledge on spectroscopic techniques to analyze (bio)molecules. Focus is on NMR and mass spectrometry techniques
- Insight into properties (e.g. structure, dynamics, spectroscopic properties) of molecules employing theoretical models. Acquisition of basic knowledge to compute molecules
- Application of laws of thermodynamics to describe chemical reactions and biological processes with a focus on binding and recognition reactions in biological systems
- Acquire basic knowledge to analyze time courses of chemical reactions and biological processes
- Acquisition of skills to work independently and self-determined in the laboratory with regard to the roles of GSP of the University of Lübeck and of the DFG-guidelines.
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Grading through: |
Requires: |
Responsible for this module: - Prof. Dr. rer. nat. Ulrich Günther
Teachers: - Prof. Dr. rer. nat. Ulrich Günther
- PD Dr. phil. nat. Thomas Weimar
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Literature: - Peter Atkins and Julio de Paula: Physical Chemistry for the Life Sciences - Oxford, University Press, Freeman and Company, 2006, ISBN 0-1992-8095-9
- Thomas Engel und Philip Reid: Physikalische Chemie - Pearson Studium, 2006, ISBN 13: 978-3-8273-7200-0
- van Holde, Johnson & HoPrentice Hall: Principles of Physical Biochemistry - New Jersey, 1998, 2006, ISBN 0-13-720459-0
- Atkins: Physical Chemistry - Oxford University Press, Oxford Mel-bourne Tokyo, 1998, ISBN 0-19-850101-3 Paperback, Deutsche Ausgabe (dritte Auflage) bei Wiley VCH, 2002: ISBN 3-527-30236-0 Wiley-VCH, Weinheim
- Fersht, W. H.: Structure and Mechanism in Protein Science - New York, 1999, ISBN 0-7167-3268-8
- Cantor & Schimmel: Biophysical Chemistry, Parts I-III - Freeman and Company, New York, 1980, ISBN 0-71671188-5 Paperback
- H. Friebolin: Ein- und zweidimensionale NMR-Spektroskopie - Wiley-VCH
- James Keeler and Peter Wothers: Chemical Structure and Reactivity: An integrated approach - Oxford University Press, 2008; second ed. 2013
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Language: |
Notes:Prerequisites for the modul: - None Prerequisites for admission to the written examination: - Successful completion of the excercises as specified at the beginning of the semester Modul exam(s): - LS2300-L1: Biophysical Chemistry, written exam, 90 min, 100 % of module grade - LS2300-L2: Practical course Biophysical Chemistry, ungraded practical course, 0 % of module grade, has to be passed MML: Optional course in the 2nd semester master program with specialisation in Life Science Biophysics: some specific practicals The practical course takes place in September as compact course. Prerequisite LS1600 and LS2600 The module is better understandable if the modules Physics 1 or 2 have been attended before. (Share of Institute of Physics in practical course is 25%.) |
Letzte Änderung: 11.4.2024 |
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