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Module Guide from winter term 2023/24

Modul EW4110-KP08

Pharmaconutrition (PharmaNM)

Duration:


1 Semester
Turnus of offer:


each winter semester
Credit points:


8
Course of studies, specific field and terms:
  • Master Nutritional Medicine 2023 (compulsory), Nutritional Sciences, 1st semester
  • Master Nutritional Medicine 2019 (compulsory), Nutritional Sciences, 1st semester
Classes and lectures:
  • Pharmacology for nutritional medicine (exercise, 2 SWS)
  • Pharmacology for nutritional medicine (lecture, 4 SWS)
Workload:
  • 120 Hours private studies
  • 90 Hours in-classroom work
Contents of teaching:
  • 1. General pharmacology
  • 1.1 Pharmacokinetics (LADME model, pharmacokinetic parameters)
  • 1.2 Pharmacodynamics (agonism/antagonism, dose-response-relationships, mechanisms of action, receptor types)
  • 1.3 Adverse drug reactions (mechanisms, risk factors, pharmacogenetics, kidney and liver injuries, prevention, ADR of herbal supplements)
  • 1.4 Drug interactions (mechanisms of drug-drug interactions and food-drug-interactions)
  • 1.5 Regulatory affairs of pharmaceuticals (new medications development, phases of clinical studies, approval, pharmacovigilance)
  • 2. Specific pharmacology in nutritional medicine
  • 2.1 Analgetics (NSAID, opioids, co-analgetics, pharmacotherapy of migraine, local anaesthetics, general anaesthetics)
  • 2.2 Gastrointestinal pharmacology (ulcer drugs, helicobacter eradication, CID drugs, laxatives, antidiarrhoeal drugs, antiemetics)
  • 2.3 Metabolic pharmacology (pharmacotherapy of diabetes, osteoporosis, obesity, cachexia, gout, dyslipidaemia, pharmacotherapy after bariatric surgery)
  • 2.4 Endocrine pharmacology (gluco- and mineralocorticoids, thyroid hormones)
  • 2.5 Cardiovascular pharmacology (antihypertensives, diuretics, RAAS inhibitors, adrenoceptor antagonists, calcium antagonists)
  • 2.6 Anticoagulants and antiplatelet medication (vitamin K antagonists, NOAC, heparin, clopidogrel, ASS)
  • 2.7 Neuropharmacology (antidepressants, antipsychotics, anxiolytics, sedatives, hypnotics)
  • 2.8 Antimicrobial pharmacology (mechanisms of action and resistance, antibiotics, antiviral drugs, antifungals)
  • 2.9 Antineoplastic pharmacology (mechanisms of action and resistance, chemotherapy, targeted therapies, endocrine therapy, adjuvant pharmacotherapy)
  • 3. Pharmaconutrition, nutraceuticals and functional food
  • 3.1 Definition and history of immunonutrition
  • 3.2 Nutraceuticals and functional food (?3 fatty acids, phytosterols, conjugated linoleic acids (CLA), structured lipids, sphingolipids, prebiotic fibres, prebiotic oligosaccharides, probiotics, folic acid, vitamin E, tocotrienols, calcium, magnesium, iron, selenium, zinc, phytochemicals)
  • 3.2 Pharmacological use of nutraceutcials (ICU, oncology, geriatrics, neurology)
  • 3.3 Effects of food ingredients and diets on pharmacological drug action (pharmacomicrobiomics, food drug interactions, radio-/chemosensitizer, short-term fasting, fasting mimetics, ketogenic diet)
  • 3.4 Effects of food ingredients on pharmacotherapy adverse effects (drug specific supplementation of nutrients)
Qualification-goals/Competencies:
  • Professional competences: The students have broad knowledge of general pharmacology and selected pharmacological fields in nutritional medicine. They are able to explain and critically discuss the underlying pharmacological principles and transfer them to innovative approaches. They have special skills in analysing complex pharmaconutritional problems and perform a critical review of current literature regarding questions of pharmaconutrition. The students can develop strategic approaches that integrate pharmacological, nutritional and technological aspects.
  • Personal competences: The students are able to discuss pharmaconutritional questions in small teams and they are capable of providing methods of resolution. They can reflect their specific knowledge, identify limitations of pharmacological studies and independently develop useful and strategic research issues.
Grading through:
  • Regular attendance at seminars
  • written exam
Responsible for this module:
  • Prof. Dr. Martin Smollich
Teachers:
  • Institute of Nutrition Medicine
  • Prof. Dr. Martin Smollich
Literature:
  • by Laurence Brunton (Author), Bruce Chabner (Author), Bjorn Knollman (Author): Goodman and Gilman's The Pharmacological Basis of Therapeutics - Mcgraw-Hill Education Ltd; 12. Edition
  • Higdon J, Drake VJ: An Evidence-based Approach to Phytochemicals and Other Dietary Factors. - Thieme; 2nd edition (2012)
  • Meyer AH (ed): Praxishandbuch Functional Food. - Behr’s Verlag, 81st edition (2019)
Language:
  • offered only in English
Notes:

Admission requirements for taking the module:
- none

Admission requirements for the module examination(s):
- Successful completion of exercises as specified at the beginning of the semester

Module examination(s):
- EW4410-L1 Pharmaconutrition, written exam, 120 min, 100 % of the grade

Letzte Änderung:
19.4.2021