Duration:
1 Semester | Turnus of offer:
each summer semester | Credit points:
3 |
Course of studies, specific field and terms: - Master Infection Biology 2018 (Module part of a compulsory module), Microbiology, 2nd semester
- Master Infection Biology 2012 (Module part of a compulsory module), Microbiology, 2nd semester
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Classes and lectures: - Rational Drug Design (lecture, 2 SWS)
| Workload: - 30 Hours in-classroom work
- 60 Hours private studies
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Contents of teaching: | - Drug development an overview
- Target identification and validation
- Role of x-ray crystallography in drug development
- Structure-based drug design Principles and methods
- Case studies of structure-based drug development
- Combinatorial approach for nucleic acid therapeutics identification
- Oligomeric nucleic acid therapeutics
- Cellular applications of nucleic acid therapeutics via non-viral carrier systems
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Qualification-goals/Competencies: - Basic strategies of drug design
- The path from the discovery of an active principle to a marketable product. Rational drug design
- NMR and crystallography as fundamental tools for finding and optimizing active agents
- Structure and effect relationships will be demonstrated using examples, techniques used for theoretical prediction and experimental proof will be introduced, especially the complementary approach using crystallographic methods and NMR experiments
- Students will critically evaluate these methods and perceive their limits
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Grading through: |
Responsible for this module: Teachers: - Prof. Dr. rer. nat. Thomas Peters
- Prof. Dr. rer. nat. Rolf Hilgenfeld
- Dr.rer.nat Sonja Petkovic
- Prof. Dr. rer. nat. Tobias Restle
- Prof. Dr. Lars Redecke
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Literature: - -: Current scientific literature
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Language: |
Notes:Part of module LS4185-KP03. The module part includes a written Test as the only form of examination. The total amount of time allocated to a written examination is usually between 60 and 180 minutes (Examination Regulations). |
Letzte Änderung: 17.7.2019 |
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