Module LS4165-KP09

Model Systems of Infection (ModSysInf)

Duration:

1 Semester

Turnus of offer:

each summer semester

Credit points:

Course of studies, specific field and terms:

Master Infection Biology 2023 (compulsory), Infection Biology, 2nd semester
Master Infection Biology 2018 (compulsory), Infection Biology, 2nd semester
Master Infection Biology 2012 (compulsory), Infection Biology, 2nd semester

Classes and lectures:

Practical course In vivo Models (practical course, 2 SWS)
Lectures In vivo Models (lecture, 3 SWS)
Excercises In vivo Models (seminar, 2 SWS)

Workload:

165 Hours private studies
105 Hours in-classroom work

Contents of teaching:

(1) Animal experimentation and biological safety; Lecture: (a) animal protection laws, animal experimentation application, documentation of animal experiments, anatomy and physiology of the mouse, breeding methods and nomenclature, transgenic mice, anesthetics, analgesia, methods of anesthesia, criteria for animal burden and experiment abortion, ethics, alternative and additional methods, biological and gene technological safety. (b) Practicals: biology and handling of mouse, handling and behaviour of mouse, health and gender controling, application methods, blood sampling and animal protection appropriate sacrifice, sectioning mouse, working under biological safety levels, transgenic technology
(2) Clinic-near model systems in infection biology: principles of animal experimentation in infection biology, infections of the skin (leishmaniasis), lung (tuberculosis, influenza), intestinal (helminths, salmonella), intracerebral (toxoplasmosis) and systemic infections (trypanosomis, malaria, sepsis), humanized animal experimental models, comparison of scientific results from animal experimentation and the situation in humans

Qualification-goals/Competencies:

Basic knowledge of laws regulating animal experimentaion; theoretical and practical basics in handling of experimental animals; basic knowledge on aspects of biological and gene technological safety; basic knowledge on the generation of transgenic animals
Basic knowledge based on experimental examples; consolidation of knowledge in seminar
Knowing how to handle the model systems; Competence in protocol writing

Grading through:

written exam

Responsible for this module:

Dr. rer. nat. Christoph Hölscher

Teachers:

Dr. rer. nat. Christoph Hölscher
Prof. Ph.D. Tamás Laskay
Prof. Dr. rer. nat. Stefan Taube
PD Dr. rer. nat. Norbert Reiling
Dr. rer. nat. Bianca Schneider
Dr. Kerstin Walter
Dr.rer.nat. Christian Karsten
Dr. rer. nat. Matthias Hauptmann
Dr. rer. nat. Kristina Ritter
Dr. rer. nat. Anke Osterloh

Language:

offered only in English

Notes:

Admission requirements for taking the module:
- None

Admission requirements for participation in module examination(s):
- Regular (85%) and successful participation in seminar and lab.

Module Examination(s):
- LS4165-L1: Model Systems of Infection, written exam, 90 min, 50% of the module grade; seminar paper and practical each 25% of the module grade.

Regular attendance of the lecture, apart from self-study, is strongly recommended as a solid preparation for the written exam.

Letzte Änderung:

21.4.2021